Premium
Inside Back Cover: Asymmetric Cascade Catalysis with Chiral Polyoxometalate‐Based Frameworks: Sequential Direct Aldol and Epoxidation Reactions (ChemCatChem 10/2017)
Author(s) -
Han Qiuxia,
Li Wenwen,
Wang Shugai,
He Jiachen,
Du Wei,
Li Mingxue
Publication year - 2017
Publication title -
chemcatchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201700742
Subject(s) - polyoxometalate , aldol reaction , catalysis , chemistry , pyrrolidine , cascade reaction , lewis acids and bases , organocatalysis , cascade , combinatorial chemistry , aldol condensation , lewis acid catalysis , enantioselective synthesis , organic chemistry , chromatography
The Cover shows two enantiomorphs of CuW–PYIs with novel Kagomé lattice as chiral catalysts for the asymmetric cascade direct aldol/epoxidation reactions by synergism of multiple catalytic sites.In their Full Paper, Q. Han, W. Li et al. demonstrate the synthesis of chiral polyoxometalate‐based frameworks consisting of a single porous coordination network that incorporates pyrrolidine as chiral organocatalyst, POM as oxidation catalyst and Cu(II) as Lewis acid catalyst. The functionalized materials are active catalysts for the synthesis of optical epoxy ketones from readily available starting materials. The compatibility between reaction intermediates and the synergy of the multiple catalytic cycles are improved by the interaction of pyrrolidine with the carbonyl group of ketones throughout the reaction, which drives the direct aldol/epoxidation cascade reaction in an orderly and asymmetrical way. More information can be found in the Full Paper by Q. Han, W. Li et al. on page 1801 in Issue 10, 2017 (DOI: 10.1002/cctc.201700160).