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Palladium‐Catalyzed Carbonylative Cyclization of Azoarenes
Author(s) -
Wang Zechao,
Yin Zhiping,
Zhu Fengxiang,
Li Yahui,
Wu XiaoFeng
Publication year - 2017
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201700679
Subject(s) - palladium , catalysis , carbonylation , regioselectivity , intramolecular force , chemistry , medicinal chemistry , combinatorial chemistry , organic chemistry , carbon monoxide
In this communication, we established an interesting palladium‐catalyzed carbonylation protocol for the intramolecular cyclization of azoarenes. With Mo(CO) 6 as the solid CO source and through C(sp 2 )−H bond activation, a series of azoarenes were transformed into the corresponding 2‐arylindazolones in moderate to good yields. Notably, not only symmetrical azoarenes, but also unsymmetrical substrates underwent the reaction with excellent regioselectivity.