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Selective Oxidation of Activated Alcohols by Supported Gold Nanoparticles under an Atmospheric Pressure of O 2 : Batch and Continuous‐Flow Studies
Author(s) -
Giorgi Pascal D.,
Elizarov Nelli,
Antoniotti Sylvain
Publication year - 2017
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201700179
Subject(s) - flow chemistry , catalysis , colloidal gold , nanoparticle , chemistry , alcohol oxidation , atmospheric pressure , selectivity , allylic rearrangement , continuous flow , heterogeneous catalysis , chemical engineering , nanotechnology , materials science , organic chemistry , oceanography , physics , geology , mechanics , engineering
In the hunt for a simple, mild, and scalable protocol for gold nanoparticle‐catalyzed oxidation of benzylic and allylic alcohols under O 2 , we have used commercially available gold nanoparticles supported on alumina to selectively oxidize a large range of activated alcohols to the corresponding carbonyl compounds in good yields (68–99 %) and with excellent selectivity (ca. 100 %). The true heterogeneous nature of the catalysis by gold was demonstrated, allowing us to further adapt this protocol to continuous‐flow reactors by using the tube‐in‐tube technology, in which higher yields were obtained thanks to an improved oxygenation of the reaction medium.