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Remarkable Acceleration of Benzimidazole Synthesis and Cyanosilylation Reactions in a Supramolecular Solid Catalyst
Author(s) -
RojasBuzo Sergio,
GarcíaGarcía Pilar,
Corma Avelino
Publication year - 2017
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201601407
Subject(s) - benzimidazole , catalysis , supramolecular chemistry , chemistry , lewis acids and bases , lewis acid catalysis , combinatorial chemistry , organic synthesis , organic chemistry , solid acid , crystal structure
A solid metal–organic catalyst with hydrophobic pockets and Lewis acid centers strongly accelerates the reaction rate for organic reactions. This is exemplified for the cyanosilylation of ketones and for the synthesis of benzimidazoles, for which very high selectivities are obtained. The solid can be recovered and reused and its behavior approaches that of a functional enzyme mimic.