Premium
Pinacol Rearrangement and Direct Nucleophilic Substitution of Allylic Alcohols Promoted by Graphene Oxide and Graphene Oxide CO 2 H
Author(s) -
GómezMartínez Melania,
Baeza Alejandro,
Alonso Diego A.
Publication year - 2017
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201601362
Subject(s) - allylic rearrangement , graphene , oxide , pinacol , nucleophilic substitution , chemistry , nucleophile , catalysis , substitution reaction , medicinal chemistry , organic chemistry , materials science , nanotechnology
Abstract Graphene oxide (GO) and carboxylic acid functionalized GO (GO–CO 2 H) have been found to efficiently promote the heterogeneous and environmentally friendly pinacol rearrangement of 1,2‐diols and the direct nucleophilic substitution of allylic alcohols. In general, high yields and regioselectivities are obtained in both reactions using 20 wt % of catalyst loading and mild reaction conditions.