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Highly Stereoselective Synthesis of Imidazolidines through the Palladium(0)‐Catalyzed Three‐Component Reaction of 2,3‐Allenylamines, Organic Halides, and Imines
Author(s) -
Hu Jinxing,
Kong Bo,
Liu Yue,
Xu Boxuan,
Zhao Yanfang,
Gong Ping
Publication year - 2017
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201601345
Subject(s) - chemistry , palladium , halide , catalysis , stereoselectivity , aryl , organic chemistry , component (thermodynamics) , organic synthesis , combinatorial chemistry , alkyl , physics , thermodynamics
A new and efficient method for the synthesis of polysubstituted imidazolidines through the Pd 0 ‐catalyzed double addition/cyclization of 2,3‐allenylamines with aryl iodides and imines was explored. This catalytic reaction afforded the desired products in good yields with high diastereoselectivities.