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KIO 3 ‐Catalyzed Domino C(sp 2 )−H Bond Sulfenylation and C−N Bond Oxygenation of Enaminones toward the Synthesis of 3‐Sulfenylated Chromones
Author(s) -
Zhong Shanshan,
Liu Yunyun,
Cao Xiaoji,
Wan JiePing
Publication year - 2017
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201601273
Subject(s) - catalysis , domino , bond cleavage , chemistry , cascade reaction , triple bond , transition metal , combinatorial chemistry , medicinal chemistry , organic chemistry , double bond
With 2‐hydroxyphenyl‐functionalized enaminones and thiophenols as the starting materials, the facile synthesis of 3‐sulfenylated chromones has been realized through a KIO 3 ‐catalyzed domino reaction of C−H sulfenylation and subsequent C−N‐cleavage‐based C−O bond formation. The reaction was performed under transition‐metal‐free conditions in ethyl lactate, a bioavailable ecofriendly medium.
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