Premium
Novel Functional Hollow and Multihollow Organic Microspheres: Enhanced Efficiency in a Complex, Heterogeneous, Asymmetric, Three‐Component/Triple Organocascade Reaction
Author(s) -
Dai Fuqiang,
Zhao Zhiwei,
Xie Guangxin,
Feng Dandan,
Ma Xuebing
Publication year - 2017
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201601120
Subject(s) - copolymer , dispersity , styrene , divinylbenzene , polymer chemistry , ethylene glycol , monomer , acrylic acid , chemistry , ethylene glycol dimethacrylate , chemical engineering , dispersion polymerization , acrylamide , materials science , polymer , organic chemistry , methacrylic acid , engineering
The pioneered construction of monodisperse hollow and multihollow Jørgensen–Hayashi‐functionalized microspheres with a well‐defined spherical morphology, high surface area, and large pore volume were developed by initial dispersion copolymerization of the Jørgensen–Hayashi organocatalyst with acrylamide and styrene monomers cross‐linked by p ‐divinylbenzene and ethylene glycol dimethacrylate, respectively, on the surface of poly(styrene/acrylic acid) (PS) microspheres to form core–shell structures, followed by removal of the PS core by etching in organic solvents. The as‐prepared hollow and multihollow microspheres were able to achieve better mass transfer in a complex heterogeneous asymmetric three‐component/triple cascade reaction and provided the products in good yields (31–61 %) with excellent stereoselectivities (80:20–93:7 dr , >99 % ee ).