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Chemoselective Transfer Hydrogenation of Aldehydes with HCOONH 4 Catalyzed by RuCl(CNN Ph )(PP) Pincer Complexes
Author(s) -
Baldino Salvatore,
Facchetti Sarah,
Nedden Hans Günter,
ZanottiGerosa Antonio,
Baratta Walter
Publication year - 2016
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201600892
Subject(s) - transfer hydrogenation , pincer movement , chemistry , catalysis , toluene , quinoline , reductive amination , amination , substrate (aquarium) , condensation , organic chemistry , medicinal chemistry , ruthenium , oceanography , physics , thermodynamics , geology
Aldehydes were chemoselectively reduced to primary alcohols by using HCOONH 4 as the hydrogen donor through transfer hydrogenation catalyzed by benzo[ h ]quinoline pincer complexes RuCl(CNN Ph )(PP) at substrate to catalyst molar ratios of 2000 to 20 000. This practical reaction performed with aldehydes of commercial‐grade purity in a water/toluene biphasic system afforded alcohols without the formation of condensation or amination side products.