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Copper(II)‐Catalyzed Direct Azidation of N ‐Acylated 8‐Aminoquinolines by Remote C−H Activation
Author(s) -
Dou Yandong,
Xie Zhenda,
Sun Zongguo,
Fang Hongli,
Shen Chao,
Zhang Pengfei,
Zhu Qing
Publication year - 2016
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201600874
Subject(s) - aminoquinolines , catalysis , chemistry , copper , combinatorial chemistry , organic chemistry , polymer chemistry , medicinal chemistry
A simple and efficient copper(II)‐catalyzed C5 azidation of N ‐acylated 8‐aminoquinolines by remote C−H activation was developed. On the basis of this reaction, a series of new C5‐azidated 8‐amidequinolines were synthesized in moderate to good yields.