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Visible‐Light Photocatalytic Aerobic Benzylic C(sp 3 )−H Oxygenations with the 3 DDQ*/ tert ‐Butyl Nitrite Co‐catalytic System
Author(s) -
Rusch Fabian,
Schober JanChristian,
Brasholz Malte
Publication year - 2016
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201600704
Subject(s) - catalysis , nitrite , chemistry , photocatalysis , benzoquinone , photochemistry , medicinal chemistry , organic chemistry , nitrate
Photocatalytic aerobic benzylic C(sp 3 )−H oxygenations of aromatic hydrocarbons and C3‐substituted indoles were studied by employing a co‐catalytic system of 3 DDQ* (DDQ=2,3‐dichloro‐5,6‐dicyano‐1,4‐benzoquinone) and tert ‐butyl nitrite. The superior efficiency of these reaction conditions was demonstrated by comparison with the analogous thermal protocol, and a range of substrates could be oxidized catalytically and selectively in good yields.