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Ytterbium(III) Trifluoromethanesulfonate Catalyzed Ring‐Opening C(sp 3 )−N Bond Formation of Benzoxazoles with Propargylic Alcohols
Author(s) -
Liu Wenfei,
Sun Yongqing,
Zhao Haiying,
Li Baoguo,
Chen Shufeng
Publication year - 2016
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201600606
Subject(s) - trifluoromethanesulfonate , benzoxazole , chemistry , catalysis , aldehyde , ytterbium , ring (chemistry) , medicinal chemistry , organic chemistry , polymer chemistry , combinatorial chemistry , materials science , optoelectronics , doping
Abstract A novel ytterbium(III) trifluoromethanesulfonate [Yb(OTf) 3 ]‐catalyzed ring‐opening C(sp 3 )−N bond formation reaction of benzoxazole with propargylic alcohols was established. This reaction uses readily available starting materials and is operationally simple; it thus represents a practical method for the construction of highly functionalized substituted benzenes bearing aldehyde, propargylamine, and hydroxy groups with high atom economy.