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Synthesis of Vinyl Carboxylic Acids using Carbon Dioxide as a Carbon Source by Iron‐Catalyzed Hydromagnesiation
Author(s) -
Santhoshkumar Rajagopal,
Hong YaChun,
Luo ChingZong,
Wu YunChing,
Hung ChenHsun,
Hwang KuenYuan,
Tu AnPang,
Cheng ChienHong
Publication year - 2016
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201600279
Subject(s) - reagent , catalysis , chemistry , carbon dioxide , hydride , carbon fibers , organic chemistry , materials science , hydrogen , composite number , composite material
An iron‐catalyzed synthesis of α,β‐unsaturated carboxylic acids from alkynes and carbon dioxide was developed. This reaction proceeds through hydromagnesiation of alkynes followed by carbon dioxide insertion under atmospheric pressure and ambient temperature in the presence of iron and a Grignard reagent as a catalyst and hydride source, respectively. Several symmetrical and unsymmetrical alkynes were transformed into the corresponding acids in good to excellent yields. The methodology provides an efficient route to the synthesis of vinyl carboxylic acids.