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Selective β‐Arylation of Thiophenes with Aryl Iodides Catalyzed by Dinuclear Palladium Carboxylate Complexes
Author(s) -
Maki Yohei,
Goto Takahiro,
Tsukada Naofumi
Publication year - 2016
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201501132
Subject(s) - iodobenzene , palladium , chemistry , aryl , conjugated system , catalysis , selectivity , carboxylate , combinatorial chemistry , organic chemistry , medicinal chemistry , polymer chemistry , polymer , alkyl
Novel dinuclear palladium complexes bearing acetoxy ligands were synthesized and characterized by X‐ray crystal analysis. The complexes were utilized for the arylation of 2‐ethylthiophene with iodobenzene to give ethylphenylthiophenes with high β selectivity. The β‐arylation was also applied to a variety of iodoarenes and thiophenes, except those bearing conjugated carbonyl substituents.