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Cover Picture: Combination of Glycosyltransferases and a Glycosynthase in Sequential and One‐Pot Reactions for the Synthesis of Type 1 and Type 2 N ‐Acetyllactosamine Oligomers (ChemCatChem 19/2015)
Author(s) -
Henze Manja,
Schmidtke Simon,
Hoffmann Natalie,
Steffens Hanna,
Pietruszka Jörg,
Elling Lothar
Publication year - 2015
Publication title -
chemcatchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201501030
Subject(s) - biocatalysis , glycoconjugate , glycosyltransferase , carbohydrate , glycan , chemistry , directed evolution , stereochemistry , enzyme , organic chemistry , biochemistry , reaction mechanism , catalysis , gene , mutant , glycoprotein
The Front Cover shows how biocatalysis and especially multi‐enzyme systems are a viable alternative for the synthesis of complex glycan structures. The proper adaptation of reaction conditions makes “juggling” with a set of enzymes possible. In their Full Paper, L. Elling et al. present novel glycoconjugates, yet not realized by chemical carbohydrate synthesis. More details can be found in the Full Paper by L. Elling et al. on page 3131 in Issue 19, 2015 (DOI: 10.1002/cctc.201500645).