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Light‐Stable Silver N‐Heterocyclic Carbene Catalysts for the Alkynylation of Ketones in Air
Author(s) -
Lazreg Faïma,
Lesieur Mathieu,
Samson Andrew J.,
Cazin Catherine S. J.
Publication year - 2016
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201500869
Subject(s) - carbene , acetylide , cationic polymerization , alkynylation , chemistry , catalysis , ligand (biochemistry) , combinatorial chemistry , photochemistry , organic chemistry , biochemistry , receptor
N‐Heterocyclic carbene (NHC) silver(I) complexes were employed efficiently in the alkynylation of ketones. These cationic complexes were highly active and efficient under mild conditions and in air without the need for an additive. The mechanism of this transformation was investigated. Experiments suggest that the formation of a silver acetylide key intermediate and the release of one ligand from the silver centre enable the transformation.