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α‐Methylenation of Methyl Propanoate by the Catalytic Dehydrogenation of Methanol
Author(s) -
Lorusso Patrizia,
Coetzee Jacorien,
Eastham Graham R.,
ColeHamilton David J.
Publication year - 2016
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201500763
Subject(s) - dehydrogenation , methanol , catalysis , anhydrous , formaldehyde , chemistry , condensation , methyl methacrylate , organic chemistry , medicinal chemistry , polymerization , physics , polymer , thermodynamics
A one‐pot system for the conversion of methyl propanoate (MeP) to methyl methacrylate (MMA) has been investigated. In particular, this study is focused on the possibility of performing catalytic dehydrogenation of methanol for the in situ production of anhydrous formaldehyde, which is then consumed in a one‐pot base‐catalysed condensation with MeP to afford methyl 3‐hydroxy‐2‐methylpropanoate, which spontaneously dehydrogenates to MMA, some of which is subsequently hydrogenated to methyl 2‐methypropanoate (M i Bu).