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(+)‐Cinchonine‐Decorated Dendrimers as Recoverable Organocatalysts
Author(s) -
Rull Jordi,
Casals Martí,
Sebastián Rosa M.,
Vallribera Adelina,
Majoral JeanPierre,
Caminade AnneMarie
Publication year - 2015
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201500580
Subject(s) - cinchonine , dendrimer , amination , chemistry , diastereomer , enantioselective synthesis , organic chemistry , combinatorial chemistry , catalysis
First‐ and fourth‐generation phosphorus dendrimers decorated on their surface with (+)‐cinchonine moieties for the use as organocatalysts have been prepared. The first‐generation dendrite showed the highest activity and enantioselectivity in the α‐amination of several β‐dicarbonyl compounds. A positive dendritic effect was observed. Its recovery and reuse over 10 cycles was demonstrated without loss of activity. Preliminary studies of the scope of the reaction have been performed.