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Polystyrene‐Supported Triphenylsilyl Chloride for the Silylation‐Based Kinetic Resolution of Secondary Alcohols
Author(s) -
Akhani Ravish K.,
Clark Robert W.,
Yuan Liang,
Wang Li,
Tang Chuanbing,
Wiskur Sheryl L.
Publication year - 2015
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201500173
Subject(s) - kinetic resolution , silylation , selectivity , chemistry , polystyrene , enantiomer , styrene , organic chemistry , chloride , polymer , resolution (logic) , alcohol , polymer chemistry , catalysis , copolymer , enantioselective synthesis , artificial intelligence , computer science
A silyl chloride derivatized styrene polymer was employed in the silylation‐based kinetic resolution of secondary alcohols for chromatography‐free separation of alcohol enantiomers. Synthetically useful selectivity factors were obtained; furthermore, the polymer was recycled for use in a subsequent kinetic resolution, and it maintained its selectivity and integrity.