Premium
Iridium(III)‐Catalyzed Benzylic Amine Directed CH Sulfonamidation of Arenes with Sulfonyl Azides
Author(s) -
Chen Heng,
Huestis Malcolm P.
Publication year - 2015
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201402944
Subject(s) - sulfonyl , chemistry , iridium , amine gas treating , catalysis , aryl , salt (chemistry) , medicinal chemistry , polymer chemistry , organic chemistry , combinatorial chemistry , alkyl
The development of a benzylic amine directed ortho ‐sulfonamidation of aryl CH bonds with sulfonyl azides was investigated. The combination of a commercially available iridium(III) complex with a silver salt gave rise to an active manifold capable of promoting efficient CN bond formation for a variety of substrates.