Premium
A New Remote Control for Traceless meta ‐CH Olefination of Phenols
Author(s) -
Martínez Claudio,
Muñiz Kilian
Publication year - 2013
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201300538
Subject(s) - nitrile , phenols , phenol , palladium , chemistry , substitution (logic) , catalysis , group (periodic table) , combinatorial chemistry , functional group , organic chemistry , computer science , programming language , polymer
Ghosting the directing group: A clever design of a nitrile based catalyst directing group, serves as tool in the palladium‐catalyzed meta ‐olefination of phenol derivatives. This group can be removed tracelessly, thus providing a convenient route to meta ‐substitution of phenols, a transformation that cannot be conducted by classic aromatic substitution chemistry.