Premium
Palladium‐Catalyzed CH ortho Arylation of Benzoic Acids with Diaryliodonium Salts in Water
Author(s) -
Wu Zhiqing,
Chen Si,
Hu Chenxu,
Li Zhengkai,
Xiang Haifeng,
Zhou Xiangge
Publication year - 2013
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201300470
Subject(s) - catalysis , palladium , aqueous medium , solvent , chemistry , aqueous solution , combinatorial chemistry , benzoic acid , organic chemistry , computer science
Get down with the func(tionalization): An efficient and practical protocol for the CH ortho arylation of benzoic acids with diaryliodonium salts by using water as an environmentally benign, nontoxic reaction medium is developed. The choice of water as the solvent is crucial for this reaction, which sets the stage for the broad application of aqueous conditions in CH functionalization reactions.