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Powerful Amino Acid Derived Bifunctional Phosphine Catalysts Bearing a Hydrogen Bond Donor in Asymmetric Synthesis
Author(s) -
Xu LiWen
Publication year - 2013
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201300198
Subject(s) - bifunctional , phosphine , chemistry , catalysis , tsuji–trost reaction , allylic rearrangement , alkylation , hydrogen bond , combinatorial chemistry , amino acid , organic chemistry , bifunctional catalyst , medicinal chemistry , molecule , biochemistry
This minireview focuses on the recent advances in the synthetic application of amino acid‐derived bifunctional phosphine catalysts bearing a hydrogen‐bond donor. In the examples illustrated, the amino acid‐based phosphines have already been proven to be versatile, catalyzing a wide range of asymmetric reactions, including (aza)‐MBH reactions, [3+2] cyclizations, [4+2] cycloadditions, allylic alkylation, and Michael addition.