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One‐Pot Production of Enantiopure Alkylamines and Arylalkylamines of Opposite Chirality Catalyzed by ω‐Transaminase
Author(s) -
Park EulSoo,
Malik M. Shaheer,
Dong JooYoung,
Shin JongShik
Publication year - 2013
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201300052
Subject(s) - enantiopure drug , chirality (physics) , amination , transaminase , catalysis , alkyl , chemistry , amine gas treating , enantioselective synthesis , organic chemistry , enzyme , physics , chiral symmetry breaking , quantum mechanics , quark , nambu–jona lasinio model
Looking for favors: The thermodynamically favorable asymmetric amination of alkyl ketones was catalyzed by ω‐transaminase with racemic arylalkylamines as an amine donor, thus affording enantiopure alkylamines and arylalkylamines of opposite chirality.