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Asymmetric Allylic Alkylation of Alkene through Direct C (sp 3 )‐H Functionalization
Author(s) -
Chen Guihua,
Chen Kang,
Shi ZhangJie
Publication year - 2013
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201300015
Subject(s) - tsuji–trost reaction , allylic rearrangement , alkene , chemistry , palladium , phosphoramidite , catalysis , alkylation , surface modification , enantioselective synthesis , combinatorial chemistry , organic chemistry , dna , biochemistry , oligonucleotide
Put your Trost in this reaction: The first catalytic asymmetric Tsuji–Trost reaction via allylic CH activation was realized using a new class of chiral phosphoramidite ligands. This work represents a considerable breakthrough in palladium catalyzed asymmetric allylic CH alkylations.