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Direct CH Bond Arylation of Indoles with Aryl Boronic Acids Catalyzed by Palladium Nanoparticles Encapsulated in Mesoporous Metal–Organic Framework
Author(s) -
Huang Yuanbiao,
Ma Tao,
Huang Ping,
Wu Dongshuang,
Lin Zujin,
Cao Rong
Publication year - 2013
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201200957
Subject(s) - aryl , catalysis , chemistry , palladium , mesoporous material , nanoparticle , boronic acid , metal , combinatorial chemistry , leaching (pedology) , selectivity , suzuki reaction , organic chemistry , nanotechnology , materials science , alkyl , environmental science , soil science , soil water
Abstract Highly dispersed Pd nanoparticles encapsulated in the mesoporous metal–organic framework MIL‐101 demonstrated high activity and selectivity for the direct C2 arylation of various indoles with aryl boronic acids using O 2 or 2,2,6,6‐tetramethylpiperidine N ‐oxyradical as an external oxidant in acidic media under mild conditions. The green catalyst is easily recoverable and can be reused six times without leaching and loss of activity.