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Copper‐Catalyzed Direct Synthesis of Benzamides from Alcohols and Amines
Author(s) -
Bantreil Xavier,
Fleith Clément,
Martinez Jean,
Lamaty Frédéric
Publication year - 2012
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201200441
Subject(s) - copper , chemistry , catalysis , primary (astronomy) , hydrochloride , organic chemistry , combinatorial chemistry , oxide , physics , astronomy
Ready, steady, copper! The efficient copper‐catalyzed formation of amides, from benzylic alcohols and hydrochloride salts of primary‐ and secondary amines, uses cheap and readily available copper oxide, as well as tert ‐butylhydroperoxide (TBHP) as an oxidant.