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Ruthenium‐Catalyzed Carbonylation of ortho CH Bonds in Arylacetamides: CH Bond Activation Utilizing a Bidentate‐Chelation System
Author(s) -
Shibata Kaname,
Hasegawa Nao,
Fukumoto Yoshiya,
Chatani Naoto
Publication year - 2012
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201200352
Subject(s) - denticity , carbonylation , chelation , chemistry , karma , moiety , catalysis , ruthenium , medicinal chemistry , combinatorial chemistry , acceptor , organic chemistry , carbon monoxide , crystal structure , philosophy , theology , buddhism , physics , condensed matter physics
Karma karma karma chelation: Direct carbonylation of CH bonds in arylacetamides was achieved using a bidentate‐chelation system. The use of 2‐pyridynylmethyl amino moiety is essential for the reaction to proceed. For achieving an efficient reaction, the presence of both ethylene (for a hydrogen acceptor) and H 2 O (probably for an efficient generation of catalytic active species) are required.