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Simple and Sustainable Copper–O 2 Chemistry towards High‐Value Products
Author(s) -
Costas Miquel
Publication year - 2012
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201100350
Subject(s) - reagent , yield (engineering) , combinatorial chemistry , chemistry , aryl , copper , organic chemistry , oxidative coupling of methane , oxidative phosphorylation , catalysis , molecular oxygen , materials science , biochemistry , alkyl , metallurgy
Oxygen meets its end, or does it? Straightforward Cu‐catalyzed preparation of α‐ketoamides has been recently achieved through oxidative coupling of aryl acetaldehydes and arylamines by using O 2 as the terminal oxidant. The work represents a remarkable example of a simple and sustainable transformation to yield elaborate and more complex biologically relevant oxidized products from readily available reagents under mild conditions.