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Site‐Selective Suzuki–Miyaura and Sonogashira Cross Coupling Reactions of the Bis(triflate) of 2,4′‐Bis(hydroxy)diphenyl Sulfone
Author(s) -
Khera Rasheed Ahmad,
Ali Asad,
Hussain Munawar,
Ibad Muhammad Farooq,
Villinger Alexander,
Langer Peter
Publication year - 2012
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201100257
Subject(s) - trifluoromethanesulfonate , sonogashira coupling , sulfone , chemistry , selectivity , coupling reaction , palladium , catalysis , organic chemistry , combinatorial chemistry , medicinal chemistry
Described is the synthesis of novel arylated and alkynylated 2,4′‐diphenyl sulfones based on what are, to the best of our knowledge, the first palladium(0)‐catalyzed cross‐coupling reactions of bis(triflates) of 2,4′‐bis(hydroxy)diphenyl sulfone. The reactions proceed with very good site‐selectivity.