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Microwave‐Assisted Meyer–Schuster Rearrangement of Propargylic Alcohols Catalyzed by the Oxovanadate Complex [V(O)Cl(OEt) 2 ]
Author(s) -
Antiñolo Antonio,
CarrilloHermosilla Fernando,
Cadierno Victorio,
GarcíaÁlvarez Joaquín,
Otero Antonio
Publication year - 2012
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201100239
Subject(s) - isomerization , catalysis , toluene , microwave irradiation , chemistry , medicinal chemistry , microwave , photochemistry , combinatorial chemistry , organic chemistry , physics , quantum mechanics
A general and efficient procedure for the selective Meyer–Schuster isomerization of both, terminal and internal alkynols, has been developed by using catalytic amounts of the readily accessible oxovanadium(V) complex [V(O)Cl(OEt) 2 ]. Reactions proceeded smoothly in toluene at 80 °C under microwave irradiation to provide the corresponding α,β‐unsaturated carbonyl compounds in excellent yields and short times without the assistance of any additive.