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Rhenium‐Catalyzed Benzannulation of o ‐Alkynylbenzaldehyde with Alkynes to Multiple 2,3‐Disubstituted Naphthalenes
Author(s) -
Umeda Rui,
Kaiba Kenta,
Morishita Shigeru,
Nishiyama Yutaka
Publication year - 2011
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201100203
Subject(s) - rhenium , naphthalene , catalysis , chemistry , steric effects , combinatorial chemistry , organic chemistry , medicinal chemistry
Bring on the super‐subs: Rhenium‐catalyzed benzannulation of o ‐alkynylbenzaldehydes and alkynes in the presence of trichloroacetic acid, afforded the corresponding 2,3‐disubstituted naphthalenes. Furthermore, this benzannulation protocol can be applied to the synthesis of multiple and sterically hindered polycyclic aromatic hydrocarbons having 2,3‐disubstituted naphthalene units.