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Metallopeptides for Enantioselective Catalysis
Author(s) -
Roelfes Gerard
Publication year - 2011
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201000413
Subject(s) - enantioselective synthesis , catalysis , dimer , chemistry , combinatorial chemistry , stereochemistry , organic chemistry
Helix the cat: Metalloenzymes are the benchmark catalysts for efficient enantioselective chemical transformations and, as such, a source of inspiration for catalyst design. Novel metallopeptides, comprising a dirhodium tetracarboxylate active site embedded in a helical peptide dimer, have been shown to catalyze highly enantioselective SiH insertion reactions.