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Functionalized Grignard Reagents in Kumada Cross‐Coupling Reactions
Author(s) -
Adrio Javier,
Carretero Juan C.
Publication year - 2010
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201000237
Subject(s) - halide , alkyl , aryl , chemistry , reagent , coupling reaction , catalysis , organic chemistry , combinatorial chemistry
Hakuna Kumada: Several efficient Kumada cross‐coupling protocols of functionalized arylmagnesium halides and functionalized aryl and alkyl halides have been recently reported, including the first examples of the catalytic asymmetric Kumada coupling of racemic secondary alkyl halides. These procedures dramatically improve the synthetic potential of the Kumada cross‐coupling reaction.