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Synthesis of Secondary Amines by Iron‐Catalyzed Reductive Amination
Author(s) -
Enthaler Stephan
Publication year - 2010
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201000180
Subject(s) - reductive amination , amination , hydride , chemistry , inert , catalysis , combinatorial chemistry , organic chemistry , hydrogen
Iron awe: For the first time, a straightforward reductive amination procedure based on iron catalysts is presented. Excellent performance is demonstrated by a system composed of FeCl 3 and poly(methylhydrosiloxane) as a cheap hydride source under non‐inert conditions. The procedure is also versatile, allowing for the amination of a wide range of substrates in yields up to 99 %.
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