Premium
A New Insight into Gold(I)‐Catalyzed Hydration of Alkynes: Proton Transfer
Author(s) -
Krauter Caroline M.,
Hashmi A. Stephen K.,
Pernpointner Markus
Publication year - 2010
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201000136
Subject(s) - counterion , proton , catalysis , solvent , chemistry , molecule , combinatorial chemistry , mechanism (biology) , organic chemistry , ion , physics , quantum mechanics
Solvent molecules have a significant impact on the mechanism of the gold(I)‐catalyzed hydration of alkynes as they enable an efficient proton transfer step. As an alternative to such a water‐assisted proton transfer, the counterion can serve as a proton shuttle. However, it seems likely that solvent molecules play a vital role for the overall reaction mechanism in either case.