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Oxidoreductases Working Together: Concurrent Obtaining of Valuable Derivatives by Employing the PIKAT Method
Author(s) -
Bisogno Fabricio R.,
RiozMartínez Ana,
Rodríguez Cristina,
Lavandera Iván,
de Gonzalo Gonzalo,
Torres Pazmiño Daniel E.,
Fraaije Marco W.,
Gotor Vicente
Publication year - 2010
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201000115
Subject(s) - enantioselective synthesis , stereoselectivity , chemistry , combinatorial chemistry , transformation (genetics) , cofactor , redox , kinetic energy , catalysis , organic chemistry , enzyme , biochemistry , gene , physics , quantum mechanics
Flying PIKATs: The stereoselective oxidation of several sulfides linked to the enantioselective oxidation of different sec ‐alcohols are combined in a parallel interconnected kinetic asymmetric transformation (PIKAT) fashion. Furthermore, the cofactor concentration employed in these processes is investigated, demonstrating a high capacity of performance, even at micromolar concentrations of the mediator.