Oxidoreductases Working Together: Concurrent Obtaining of Valuable Derivatives by Employing the PIKAT Method | Zendy

Bisogno Fabricio R. | Zendy; RiozMartínez Ana | Zendy; Rodríguez Cristina | Zendy; Lavandera Iván | Zendy; de Gonzalo Gonzalo | Zendy; Torres Pazmiño Daniel E. | Zendy; Fraaije Marco W. | Zendy; Gotor Vicente | Zendy

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Oxidoreductases Working Together: Concurrent Obtaining of Valuable Derivatives by Employing the PIKAT Method

Author(s) -

Bisogno Fabricio R.,

RiozMartínez Ana,

Rodríguez Cristina,

Lavandera Iván,

de Gonzalo Gonzalo,

Torres Pazmiño Daniel E.,

Fraaije Marco W.,

Gotor Vicente

Publication year - 2010

Publication title -

chemcatchem

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.497

H-Index - 106

eISSN - 1867-3899

pISSN - 1867-3880

DOI - 10.1002/cctc.201000115

Subject(s) - enantioselective synthesis , stereoselectivity , chemistry , combinatorial chemistry , transformation (genetics) , cofactor , redox , kinetic energy , catalysis , organic chemistry , enzyme , biochemistry , gene , physics , quantum mechanics

Flying PIKATs: The stereoselective oxidation of several sulfides linked to the enantioselective oxidation of different sec ‐alcohols are combined in a parallel interconnected kinetic asymmetric transformation (PIKAT) fashion. Furthermore, the cofactor concentration employed in these processes is investigated, demonstrating a high capacity of performance, even at micromolar concentrations of the mediator.

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