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Amination of Aliphatic Alcohols and Diols with an Iridium Pincer Catalyst
Author(s) -
Andrushko Natalia,
Andrushko Vasyl,
Roose Peter,
Moonen Kristof,
Börner Armin
Publication year - 2010
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201000046
Subject(s) - chemistry , amination , organic chemistry , alkylation , catalysis , alkyl , reductive amination , hydroamination , pincer movement , organic synthesis , combinatorial chemistry , reagent
Best aminated feature: Catalytic transformation of alcohols to amines is a fundamental transformation in synthetic organic chemistry. A general salt‐free Ir‐catalyzed amination of aliphatic alcohols and diols has been developed, which gives amino alcohols with high selectivity. By use of an Ir–pincer chlorodihydride complex, usually applied for the transfer hydrogenation of ketones, simple monoalcohols are aminated with excellent yields.