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Palladium‐Catalyzed Enantioselective Hydrosilylation of Aromatic Olefins
Author(s) -
Junge Kathrin,
Wendt Bianca,
Enthaler Stephan,
Beller Matthias
Publication year - 2010
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.200900263
Subject(s) - hydrosilylation , palladium , phosphoramidite , enantioselective synthesis , denticity , catalysis , chemistry , ligand (biochemistry) , organic chemistry , crystal structure , dna , biochemistry , receptor , oligonucleotide
All you need is H8: Palladium‐catalyzed asymmetric hydrosilylation of CC double bonds is carried out using monodentate H8‐phosphoramidite ligands. High yields and enantioselectivities up to 90 % ee are achieved under mild conditions for a broad range of substituted styrenes. A correlation between the enantioselectivity and electronic properties of the ligand was demonstrated by NMR spectroscopy.