Open AccessA novel KRAS gene mutation report in sporadic colorectal cancer, from Northwest of Iran
Author(s) -
Dolatkhah Roya,
Somi Mohammad Hossein,
Kermani Iraj Asvadi,
Farassati Faris,
Dastgiri Saeed
Publication year - 2017
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.779
Subject(s) - medicine , kras , colorectal cancer , mutation , gene , oncology , cancer research , cancer , genetics , biology
Key Clinical Message While the role of KRAS gene mutations has been widely accepted for predicting responses to anti‐ EGFR therapy in patients with colorectal cancer, although this study was based on observation of a single case it gives hope that some KRAS gene mutation may have favorable prognosis. More studies are required on patients with similar mutation to validate this finding.