Open AccessA case of chronic myelogenous leukemia with the T315I mutation who progressed to myeloid blast phase and was successfully treated with asciminib
Author(s) -
Tomassetti Sarah,
Lee Jennifer,
Qing Xin
Publication year - 2022
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.6478
Subject(s) - medicine , chronic myelogenous leukemia , myeloid leukemia , ponatinib , mutation , blast crisis , leukemia , cytotoxic t cell , immunology , cancer research , dasatinib , gene , genetics , imatinib , biology , in vitro
Patients with chronic myelogenous leukemia (CML) harboring the T315I mutation who progress to blast phase CML while on ponatinib may be successfully treated with asciminib monotherapy following induction therapy with cytotoxic chemotherapy.