Open AccessNTRK3 mutation in secretory carcinoma of the parotid gland: A Case report
Author(s) -
AlKaabba Fahad,
Alloghbi Abdurahman,
Deajim Yazeed,
Sukkari Mohamad W.,
Khan Mir Yousufuddin Ali,
Sukari Ammar
Publication year - 2022
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.6243
Subject(s) - histopathology , medicine , parotid gland , etv6 , carcinogenesis , pathology , salivary gland , carcinoma , acinic cell carcinoma , cancer , gene , biology , mucoepidermoid carcinoma , genetics , chromosomal translocation
Mammary analog secretory carcinoma (MASC) is a newly described carcinoma with a molecular hallmark of ETV6‐NTRK3 fusion that promotes oncogenesis. While MASC histopathology was well‐studied in the literature, clinical behavior remains unstudied. We present a 22‐year‐old man with painless parotid mass, which was diagnosed as salivary gland cancer, MASC subtype.