Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls | Zendy

Pähler vor der Holte Anja | Zendy; Welkoborsky´ HansJürgen | Zendy

Open Access

Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls

Author(s) -

Pähler vor der Holte Anja,

Welkoborsky´ HansJürgen

Publication year - 2022

Publication title -

clinical case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.21

H-Index - 9

ISSN - 2050-0904

DOI - 10.1002/ccr3.6057

Subject(s) - medicine , langerhans cell histiocytosis , otitis , histiocytosis , temporal bone , differential diagnosis , pathology , rare disease , effusion , biopsy , granulomatous inflammation , disease , medical diagnosis , dermatology , surgery

A 4‐year‐old girl was admitted to hospital with disturbance of balance. After being questioned, parents remembered an otitis with effusion 3 months earlier. CT‐scans revealed destruction of both temporal bones. Initial biopsy showed granulomatous, necrotic inflammation, which led to comprehensive differential diagnoses. A second tissue sample confirmed Langerhans cell histiocytosis.

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