Open AccessCase report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls
Author(s) -
Pähler vor der Holte Anja,
Welkoborsky´ HansJürgen
Publication year - 2022
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.6057
Subject(s) - medicine , langerhans cell histiocytosis , otitis , histiocytosis , temporal bone , differential diagnosis , pathology , rare disease , effusion , biopsy , granulomatous inflammation , disease , medical diagnosis , dermatology , surgery
A 4‐year‐old girl was admitted to hospital with disturbance of balance. After being questioned, parents remembered an otitis with effusion 3 months earlier. CT‐scans revealed destruction of both temporal bones. Initial biopsy showed granulomatous, necrotic inflammation, which led to comprehensive differential diagnoses. A second tissue sample confirmed Langerhans cell histiocytosis.