Open AccessAcute liver failure due to hepatitis B virus reactivation induced by doxorubicin and cyclophosphamide chemotherapy for adjuvant treatment of breast cancer: A case report
Author(s) -
Hakami Tahir
Publication year - 2022
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.5894
Subject(s) - medicine , doxorubicin , coagulopathy , jaundice , chemotherapy , cyclophosphamide , breast cancer , elevated transaminases , gastroenterology , hepatic encephalopathy , toxic hepatitis , hepatitis a virus , encephalopathy , liver failure , cancer , surgery , hepatitis , immunology , virus , cirrhosis
Acute liver failure developed in a 48‐year‐old woman within days after she received adjuvant chemotherapy for breast cancer. On arrival at ED, she had severe encephalopathy and jaundice. Serum analyses demonstrated coagulopathy and markedly increased transaminases. She was admitted to the ICU for supportive treatment but died several days later.