Open AccessSuccessful treatment with bortezomib for refractory fever associated with myelodysplastic syndrome with underlying lymphoplasmacytic lymphoma
Author(s) -
Motomura Yotaro,
Umezawa Yoshihiro,
Arimatsu Tomoyuki,
Okada Keigo,
Miura Osamu,
Kumagai Takashi
Publication year - 2022
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.5372
Subject(s) - medicine , bortezomib , lymphoplasmacytic lymphoma , chemotherapy , waldenstrom macroglobulinemia , lymphoma , refractory (planetary science) , lenalidomide , oncology , multiple myeloma , physics , astrobiology
We report a case of fever of unknown origin in a patient with MDS associated with IgM‐MGUS. The patient was positive for MYD88 mutation, and chemotherapy for LPL/WM improved the fever. Analysis of MYD88 and the effect of chemotherapy on LPL/WM finally revealed the latent LPL/WM in this case.