Open AccessA prognostic approach on a case of pediatric Philadelphia chromosome‐positive acute lymphoblastic leukemia with monosomy‐7
Author(s) -
Skhoun Hanaa,
Khattab Mohammed,
Belkhayat Aziza,
Takki Chebihi Zahra,
Dakka Nadia,
El Baghdadi Jamila
Publication year - 2021
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.5207
Subject(s) - monosomy , medicine , immunophenotyping , lymphoblastic leukemia , chromosome 7 (human) , bone marrow , pediatrics , chromosome , oncology , leukemia , karyotype , genetics , immunology , flow cytometry , biology , gene
In this work, we present the first case of a Ph‐positive ALL Moroccan girl with t (9;22)(q34;q11) and monosomy‐7. She was diagnosed with Ph‐positive ALL based on bone marrow examination, immunophenotyping, and cytogenetic analysis. She relapsed after treatment with the persistence of the Ph chromosome and the appearance of a monosomy‐7.