Open AccessMaturity‐onset diabetes of the young (MODY) due to PDX1 mutation in a sib‐pair diabetes family from Qatar
Author(s) -
Haris Basma,
Mohammed Idris,
Syed Najeeb,
Fakhro Khalid,
Hussain Khalid
Publication year - 2021
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.5141
Subject(s) - medicine , diabetes mellitus , pdx1 , maturity onset diabetes of the young , mutation , hnf1a , endocrinology , pediatrics , type 2 diabetes , genetics , gene , biology , islet
Maturity‐onset diabetes of young (MODY) is an autosomal dominant genetic disorder that causes insulin deficiency without autoimmunity. We present the first family with pancreatic duodenal homeobox 1 (PDX1) mutation causing diabetes from Qatar. Routine genetic screening of all antibody‐negative diabetic patients with diabetes should be offered to avoid misdiagnosis.