
Is chemoimmunotherapy a game changer in the treatment of locally advanced head and neck squamous cell carcinoma?
Author(s) -
Masuda Muneyuki,
Nagata Ryozaburo,
Hara Hirotaka,
Kuroki Keiji,
Sato Kuniaki,
Rikimaru Fumihide,
Toh Satoshi,
Higaki Yuichiro
Publication year - 2021
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.4793
Subject(s) - chemoimmunotherapy , medicine , pembrolizumab , head and neck squamous cell carcinoma , oncology , head and neck , chemotherapy , basal cell , head and neck cancer , cancer , surgery , immunotherapy , cyclophosphamide
Pembrolizumab and chemotherapy (chemoimmunotherapy) were administered to 2 head and neck squamous cell carcinoma (HNSCC) patients with extremely advanced local tumors and distant metastases with palliative intent. However, they demonstrated strikingly good responses and achieved remission. Expanded application of induction chemoimmunotherapy may be useful for locally advanced HNSCC.