Open AccessThe first reported case of Noonan syndrome complicated with hepatocellular carcinoma
Author(s) -
Kakizaki Satoru,
Uehara Daisuke,
Tojima Hiroki,
Suga Takayoshi,
Yamazaki Yuichi,
Sato Ken,
Kubo Norio,
Shirabe Ken,
Yokota Takayuki,
Shibuya Kei,
Maehara Tatsurou,
Yokoo Hideaki,
Naganuma Atsushi,
Uraoka Toshio
Publication year - 2021
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.4317
Subject(s) - noonan syndrome , medicine , hepatocellular carcinoma , mutation , genetic disorder , gene , cancer research , pathology , genetics , disease , biology
Noonan syndrome is a genetic multisystem disorder and is associated with mutation of genes encoding the proteins in the RAS‐MAPK pathway. We reported the first case of Noonan syndrome complicated with hepatocellular carcinoma.