Open AccessTransition of maternal serum concentration of digoxin and flecainide in the third trimester—A case report of fetal supraventricular tachycardia with hydrops
Author(s) -
Takatsuka Hirokazu,
Wakabayashi Kayo,
Yamazaki Shingo,
Tanaka Hirokazu,
Omoto Akiko,
Suzuki Takaaki,
Shozu Makio,
Ishii Itsuko
Publication year - 2021
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.3992
Subject(s) - flecainide , medicine , transplacental , digoxin , supraventricular tachycardia , third trimester , fetus , tachycardia , cardiology , anesthesia , pregnancy , heart failure , atrial fibrillation , biology , placenta , genetics
Abstract When transplacental therapy is conducted, the maternal serum concentrations of digoxin and flecainide may fluctuate throughout third trimester. Therefore, TDM may be effective in improving the efficacy and safety of treatment.